v2.7.0 - Major Release

CHANGES IN VERSION 2.7.0

NEW FEATURES

o New parameters - FILTER_HIGH_COUNT_PERC / FILTER_LOW_COUNT_PERC to filter out extreme count before normalization. Note that the parameter SPARSE_FILTERING is now deprecated and replaced by FILTER_LOW_COUNT_PERC

o New utility ; digest_genome.py which take a fasta file and the name(s) or sequence(s) of the restriction enzyme(s) in order to generate the list of restriction fragments after genome digestion.

o HiC-Pro is now able to process data generate from protocols without restriction enzyme such as DNase Hi-C. See the manual for more information

SIGNIFICANT USER-VISIBLE CHANGES

o The mapping step2 is now optional and will be run only if the ligation site is specified

o New parameter MIN_CIS_DIST in order to discard all contacts below the specified distance. This is mainly used for DNase Hi-C to remove artefact which are likely to be self ligation product.

BUG FIXES

o Fix bug in plot scale