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update manual
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nservant committed Sep 24, 2015
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4 changes: 2 additions & 2 deletions README.rst
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What is HiC-Pro ?
=================

| HiC-Pro was designed to process Hi-C data, from raw fastq files (paired-end Illumina data) to the normalized contact maps. Since version 2.6.1, HiC-Pro can analyse data from digestion protocols as well as data from protocols that do not require restriction enzyme such as DNase Hi-C.
| HiC-Pro was designed to process Hi-C data, from raw fastq files (paired-end Illumina data) to the normalized contact maps. Since version 2.7.0, HiC-Pro can analyse data from digestion protocols as well as data from protocols that do not require restriction enzyme such as DNase Hi-C.
| The pipeline is flexible, scalable and optimized. It can operate either on a single laptop or on a computational cluster using the PBS-Torque scheduler. HiC-Pro is sequential and each step of the workflow can be run independantly.
| HiC-Pro includes a fast implementatation of the ICE normalization method (see the `iced <https://github.com/hiclib/iced>`_ python library for more information).
| In addition, HiC-Pro can use phasing data to build :ref:`allele specific contact maps <AS>`.
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usage : HiC-Pro -i INPUT -o OUTPUT -c CONFIG [-s ANALYSIS_STEP] [-p] [-h] [-v]
Use option -h|--help for more information
HiC-Pro 2.6.1
HiC-Pro 2.7.0
---------------
OPTIONS
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2 changes: 1 addition & 1 deletion doc/FAQ.rst
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* The restriction fragments file has to be generated according to the reference genome, and the restriction enzyme(s) used to generate the Hi-C data.

| Since version 2.6.1, HiC-Pro proposes the utility *digest_genome.py* to generate this file using as input, the fasta file and the name(s) or sequence(s) of the restriction enzyme(s).
| Since version 2.7.0, HiC-Pro proposes the utility *digest_genome.py* to generate this file using as input, the fasta file and the name(s) or sequence(s) of the restriction enzyme(s).
| See the :ref:`HiC-Pro Utilities <UTILS>` section for more details.
| Another way is to generate the list of restriction fragments is to use the `HiTC <http://bioconductor.org/packages/release/bioc/html/HiTC.html>`_ BioConductor package.
| Note that this method only works for the genomes which are already available in BioConductor and for one restriction enzyme.
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6 changes: 3 additions & 3 deletions doc/MANUAL.rst
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.. Nicolas Servant
.. HiC-Pro
.. v2.6.1
.. v2.7.0
.. 15-09-02
HiC-Pro Manual
******************
Modified - 09th September 2015
Reference version - HiC-Pro 2.6.1
Reference version - HiC-Pro 2.7.0

Setting the configuration file
==============================
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usage : HiC-Pro -i INPUT -o OUTPUT -c CONFIG [-s ANALYSIS_STEP] [-p] [-h] [-v]
Use option -h|--help for more information
HiC-Pro 2.6.0
HiC-Pro 2.7.0
---------------
OPTIONS
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