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62 changes: 22 additions & 40 deletions README.md
Original file line number Diff line number Diff line change
Expand Up @@ -12,47 +12,29 @@ Foldseek enables fast and sensitive comparisons of large protein structure sets.
[Kim W, Mirdita M, Levy Karin E, Gilchrist CLM, Schweke H, Söding J, Levy E, and Steinegger M. Rapid and Sensitive Protein Complex Alignment with Foldseek-Multimer. bioRxiv, doi:10.1101/2024.04.14.589414 (2024)](https://www.biorxiv.org/content/10.1101/2024.04.14.589414v1)

# Table of Contents

<!-- no toc -->
- [Foldseek](#foldseek)
- [Publications](#publications)
- [Table of Contents](#table-of-contents)
- [Webserver](#webserver)
- [Installation](#installation)
- [Memory requirements](#memory-requirements)
- [Tutorial Video](#tutorial-video)
- [Documentation](#documentation)
- [Quick start](#quick-start)
- [Search](#search)
- [Output Search](#output-search)
- [Tab-separated](#tab-separated)
- [Superpositioned Cα only PDB files](#superpositioned-cα-only-pdb-files)
- [Interactive HTML](#interactive-html)
- [Important search parameters](#important-search-parameters)
- [Alignment Mode](#alignment-mode)
- [Structure search from FASTA input](#structure-search-from-fasta-input)
- [Databases](#databases)
- [Create custom databases and indexes](#create-custom-databases-and-indexes)
- [Cluster](#cluster)
- [Output Cluster](#output-cluster)
- [Tab-separated cluster](#tab-separated-cluster)
- [Representative fasta](#representative-fasta)
- [All member fasta](#all-member-fasta)
- [Important cluster parameters](#important-cluster-parameters)
- [Multimersearch](#multimersearch)
- [Using Multimersearch](#using-multimersearch)
- [Multimer Search Output](#multimer-search-output)
- [Tab-separated-complex](#tab-separated-complex)
- [Complex Report](#complex-report)
- [Multimercluster](#multimercluster)
- [Output MultimerCluster](#output-multimercluster)
- [Tab-separated multimercluster](#tab-separated-multimercluster)
- [Representative multimer fasta](#representative-multimer-fasta)
- [Filtered search result](#filtered-search-result)
- [Important multimer cluster parameters](#important-multimer-cluster-parameters)
- [Main Modules](#main-modules)
- [Examples](#examples)
- [Rescore aligments using TMscore](#rescore-aligments-using-tmscore)
- [Query centered multiple sequence alignment](#query-centered-multiple-sequence-alignment)
- [Webserver](#webserver)
- [Installation](#installation)
- [Memory requirements](#memory-requirements)
- [Tutorial Video](#tutorial-video)
- [Documentation](#documentation)
- [Quick Start](#quick-start)
- [Search](#search)
- [Output](#output-search)
- [Important Parameters](#important-search-parameters)
- [Alignment Mode](#alignment-mode)
- [Structure search from FASTA input](#structure-search-from-fasta-input)
- [Databases](#databases)
- [Create Custom Databases and Indexes](#create-custom-databases-and-indexes)
- [Cluster](#cluster)
- [Output](#output-cluster)
- [Important Parameters](#important-cluster-parameters)
- [Multimer](#multimersearch)
- [Output](#multimer-search-output)
- [MultimerCluster](#multimercluster)
- [Main Modules](#main-modules)
- [Examples](#examples)

## Webserver
Search your protein structures against the [AlphaFoldDB](https://alphafold.ebi.ac.uk/) and [PDB](https://www.rcsb.org/) in seconds using the Foldseek webserver ([code](https://github.com/soedinglab/mmseqs2-app)): [search.foldseek.com](https://search.foldseek.com) 🚀
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