Q-nexus release

ChIP-nexus, an extension of the ChIP-exo protocol, requires less input DNA and enables selective PCR duplicate removal using random barcodes. We developed a comprehensive software package for ChIP-nexus data that exploits the random barcodes used in the ChIP-nexus protocol. Furthermore, we developed bespoke methods to estimate the length of the protected region resulting from protein-DNA binding as well as for peak calling.

ChIP-nexus upgrade

Additional software for the preprocessing (from fastq to bam) has been added. In addition, the Q program has been extended by a Q nexus mode. A detailed description will soon be given in a corresponding publication and in a tutorial for the analysis of ChIP-nexus data.

Q is now able to read paired-end data

Q is now able to read paired-end data. The analysis has not changed. Reads are treated as single-end data.

In addition the linking problem with zlib has been addressed and a pre-compiled for Linux has been added to the repository.

First release

v1.0.0

Revised license file