Fig7D_(MF-EPSP).hoc

load_file("E807.hoc")

/******************************************************************/
// Insert passive & active conductances
/******************************************************************/
Vrest = -70
ins_pasive()
ins_active()
mesh_init()

/******************************************************************/
// Main Setup for EPSP
/******************************************************************/
// Setup synapse
Ndsyn = 6    // No of syn to be stim'd
NAratio = 0.2 // NMDA-to-AMPA ratio
atau = 1.5	// rise time of I_AMPA
ntau = 16   // decay tau of Inmda
tauD = 100	// Recovery of RRP in ms
tauF = 50   // decay of Af in ms
p0 = 0.2    // basal rls prob.
Af = 1 	//postAP facilitation inc / pb
//
taudmf = 20
taufmf = 50 //100
p0mf = 0.05
Afmf = 2 //1
//
ns = new NetStim(0.5)
ns.start = 10 //StimInit
ns.number = 5 //StimN
ns.interval = 20 //StimIntv, 50 Hz
tstop = 4*ns.start + ns.number * ns.interval + 500
//

wt[1] = 5.0e-4/p0mf  // MF, atau*1
wt[2] = 1.0e-4/p0    // AC, atau*1
wt[3] = 1.9e-4/p0    // PP, atau*1

/******************************************************************/
// Run EPSP
/******************************************************************/
//
synloc = 1     	// 1: MF input, 2: AC, 3: PP.
gheight = 50	// graph height in mV
graphepsp()
gepsp.begin()
setupsynapse(0)  //0: distributed; 1: single branch

// control
runsyn(synloc, 1)  //run(synloc, overlap)

// low Gkd
condkd(0.1)
runsyn(synloc, 1)

// low Gkd && low dendritic Na channel
condNa(0.5)
runsyn(synloc, 1)

// low dendritic Na channel
condkd(1)
condNa(0.5)
runsyn(synloc, 1)