-
Notifications
You must be signed in to change notification settings - Fork 4
Commit
This commit does not belong to any branch on this repository, and may belong to a fork outside of the repository.
Include nucleus targeted nanoparticle models
- Loading branch information
Marc Hahn
committed
Mar 24, 2021
1 parent
17ef3cd
commit 5d1b635
Showing
6 changed files
with
285 additions
and
71 deletions.
There are no files selected for viewing
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
Original file line number | Diff line number | Diff line change |
---|---|---|
@@ -0,0 +1,44 @@ | ||
#### CELL #### | ||
s:Ge/MyCell/Type="TsSphericalCellSphericalNP" | ||
s:Ge/MyCell/Material="Cytoplasm" | ||
s:Ge/MyCell/Parent="World" | ||
d:Ge/MyCell/CellRadius= 5.0 um | ||
s:Ge/MyCell/Color="white" | ||
|
||
#NUCLEUS | ||
d:Ge/MyCell/Nucleus/NucleusRadius= 3.0 um | ||
s:Ge/MyCell/Nucleus/Material="Nucleoplasm" | ||
d:Ge/MyCell/Nucleus/translateX = 0.0 um | ||
d:Ge/MyCell/Nucleus/translateY = 0.0 um | ||
d:Ge/MyCell/Nucleus/translateZ = 0.0 um | ||
s:Ge/MyCell/Nucleus/DrawingStyle="wireframe" | ||
s:Ge/MyCell/Nucleus/Color="red" | ||
|
||
#MITOCHONDRIA - optional | ||
i:Ge/MyCell/Mitochondria/NumberOfMitochondria= 10 | ||
d:Ge/MyCell/Mitochondria/r= 500 nm | ||
s:Ge/MyCell/Mitochondria/Material="Cytoplasm" | ||
s:Ge/MyCell/Mitochondria/Color="grass" | ||
s:Ge/MyCell/Mitochondria/DrawingStyle="wireframe" | ||
|
||
#MEMBRANE - optional | ||
d:Ge/MyCell/Membrane/Thickness = 10.0 nm | ||
s:Ge/MyCell/Membrane/Material="Cytoplasm" | ||
s:Ge/MyCell/Membrane/Color="grass" | ||
s:Ge/MyCell/Membrane/DrawingStyle="wireframe" | ||
|
||
#NANOPARTICLES in the cytosol - optional | ||
i:Ge/MyCell/Nanoparticle/NumberOfNanoparticles = 1000 | ||
d:Ge/MyCell/Nanoparticle/r = 50 nm | ||
s:Ge/MyCell/Nanoparticle/Material = "Gold" | ||
s:Ge/MyCell/Nanoparticle/Color = "yellow" | ||
s:Ge/MyCell/Nanoparticle/DrawingStyle = "solid" | ||
|
||
#NANOPARTICLES at the nucleus - optional | ||
i:Ge/MyCell/Nanoparticle/NumberOfNanoparticlesAtNucleus=500 | ||
|
||
#NANOPARTICLES at the mitochondria - optional | ||
i:Ge/MyCell/Nanoparticle/NumberOfNanoparticlesAtMitochondria=100 | ||
|
||
#The total number of nanoparticles is 1600 here | ||
#all with the same radius, material etc |
86 changes: 86 additions & 0 deletions
86
examples/TSSphericalCellNP_targetedNP_minimal_example.topas
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
Original file line number | Diff line number | Diff line change |
---|---|---|
@@ -0,0 +1,86 @@ | ||
#### GENERAL #### | ||
i:Ts/Seed = 1 #starting random seed | ||
i:Ts/NumberOfThreads = -1 | ||
b:Ts/DumpParameters = "True" | ||
Ts/PauseBeforeQuit = "False" | ||
|
||
|
||
#### GUI #### | ||
s:Gr/ViewA/Type = "OpenGL" | ||
i:Gr/ViewA/WindowSizeX = 1200 | ||
i:Gr/ViewA/WindowSizeY = 1000 | ||
u:Gr/ViewA/Zoom = 2. | ||
Ts/UseQt = "True" | ||
|
||
#### MATERIALS #### | ||
#Pure gold | ||
sv:Ma/Gold/Components = 1 "Gold" | ||
uv:Ma/Gold/Fractions = 1 1.0 | ||
d:Ma/Gold/Density = 19.32 g/cm3 | ||
s:Ma/Gold/DefaultColor = "yellow" | ||
|
||
#Cell cytoplasm | ||
sv:Ma/Cytoplasm/Components = 4 "Hydrogen" "Carbon" "Nitrogen" "Oxygen" | ||
uv:Ma/Cytoplasm/Fractions = 4 0.1025 0.1225 0.0425 0.7325 | ||
d:Ma/Cytoplasm/Density = 1.0 g/cm3 | ||
s:Ma/Cytoplasm/DefaultColor = "blue" | ||
|
||
#Cell Nucleoplasm | ||
sv:Ma/Nucleoplasm/Components = 6 "Hydrogen" "Carbon" "Nitrogen" "Oxygen" "Sulfur" "Potassium" | ||
uv:Ma/Nucleoplasm/Fractions = 6 0.106 0.09 0.032 0.742 0.004 0.026 | ||
d:Ma/Nucleoplasm/Density = 1.0 g/cm3 | ||
s:Ma/Nucleoplasm/DefaultColor = "red" | ||
|
||
|
||
#### WORLD #### | ||
s:Ge/World/Type = "TsBox" | ||
d:Ge/World/HLX = 6. um | ||
d:Ge/World/HLY = 6. um | ||
d:Ge/World/HLZ = 6. um | ||
s:Ge/World/Material = "Vacuum" | ||
|
||
|
||
#### CELL #### | ||
s:Ge/MyCell/Type="TsSphericalCellSphericalNP" | ||
s:Ge/MyCell/Material="Cytoplasm" | ||
s:Ge/MyCell/Parent="World" | ||
d:Ge/MyCell/CellRadius= 5.0 um | ||
s:Ge/MyCell/Color="white" | ||
|
||
#NUCLEUS | ||
d:Ge/MyCell/Nucleus/NucleusRadius= 3.0 um | ||
s:Ge/MyCell/Nucleus/Material="Nucleoplasm" | ||
d:Ge/MyCell/Nucleus/translateX = 0.0 um | ||
d:Ge/MyCell/Nucleus/translateY = 0.0 um | ||
d:Ge/MyCell/Nucleus/translateZ = 0.0 um | ||
s:Ge/MyCell/Nucleus/DrawingStyle="solid" | ||
s:Ge/MyCell/Nucleus/Color="red" | ||
|
||
#MITOCHONDRIA - optional | ||
i:Ge/MyCell/Mitochondria/NumberOfMitochondria= 100 | ||
d:Ge/MyCell/Mitochondria/r= 300 nm | ||
s:Ge/MyCell/Mitochondria/Material="Cytoplasm" | ||
s:Ge/MyCell/Mitochondria/Color="grass" | ||
s:Ge/MyCell/Mitochondria/DrawingStyle="wireframe" | ||
|
||
#MEMBRANE - optional | ||
d:Ge/MyCell/Membrane/Thickness = 10.0 nm | ||
s:Ge/MyCell/Membrane/Material="Cytoplasm" | ||
s:Ge/MyCell/Membrane/Color="grass" | ||
s:Ge/MyCell/Membrane/DrawingStyle="wireframe" | ||
|
||
#NANOPARTICLES in the cytosol - optional | ||
i:Ge/MyCell/Nanoparticle/NumberOfNanoparticles = 1000 | ||
d:Ge/MyCell/Nanoparticle/r = 50 nm | ||
s:Ge/MyCell/Nanoparticle/Material = "Gold" | ||
s:Ge/MyCell/Nanoparticle/Color = "yellow" | ||
s:Ge/MyCell/Nanoparticle/DrawingStyle = "solid" | ||
|
||
#NANOPARTICLES at the nucleus - optional | ||
i:Ge/MyCell/Nanoparticle/NumberOfNanoparticlesAtNucleus=500 | ||
|
||
#NANOPARTICLES at the mitochondria - optional | ||
i:Ge/MyCell/Nanoparticle/NumberOfNanoparticlesAtMitochondria=100 | ||
|
||
#The total number of nanoparticles is 1600 here | ||
#all with the same radius, material etc |
Oops, something went wrong.