diff --git a/.github/workflows/test.yaml b/.github/workflows/test.yaml
index 76ee1c6b8..dd1dcdecc 100644
--- a/.github/workflows/test.yaml
+++ b/.github/workflows/test.yaml
@@ -59,7 +59,7 @@ jobs:
           PLATFORM: ${{ matrix.os }}
           DISPLAY: :42
         run: |
-          coverage run -m pytest -v --color=yes
+          coverage run -m pytest -v --color=yes -m "not gpu"
       - name: Report coverage
         run: |
           coverage report
diff --git a/pyproject.toml b/pyproject.toml
index fa27fcd8a..435cf027c 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -107,7 +107,8 @@ xfail_strict = true
 # ]
 markers = [
     "conda: marks a subset of tests to be ran on the Bioconda CI.",
-    "extra: marks tests that require extra dependencies."
+    "extra: marks tests that require extra dependencies.",
+    "gpu: mark test to run on GPU",
 ]
 minversion = 6.0
 norecursedirs = [ '.*', 'build', 'dist', '*.egg', 'data', '__pycache__']
diff --git a/src/scirpy/tests/test_ir_dist_metrics.py b/src/scirpy/tests/test_ir_dist_metrics.py
index 6cda3c7c6..c12d8768b 100644
--- a/src/scirpy/tests/test_ir_dist_metrics.py
+++ b/src/scirpy/tests/test_ir_dist_metrics.py
@@ -745,7 +745,7 @@ def test_tcrdist_histogram_not_implemented():
         seqs = np.array(["AAAA", "AA", "AABB", "ABA"])
         _ = tcrdist_calculator.calc_dist_mat(seqs, seqs)
 
-
+@pytest.mark.gpu
 def test_gpu_hamming_reference():
     # test hamming distance against reference implementation
     from . import TESTDATA