asbestos can currently only hook processes compiled for the same architecture as itself. This will likely require a build script on either asbestos or asbestos-cli to build both 64-bit and 32-bit payloads.
IsWow64Process2 is likely the function to use to detect if a given process is 64-bit or 32-bit.
IsWow64GuestMachineSupported may also be of use here.
ShellExecuteandShellExecuteEx. Would likely require hookingShellExecuteand redirecting it toShellExecuteEx.