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The meaning of 'tml' in the 'dndscv.R' #80

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Sunsq1997 opened this issue May 26, 2022 · 0 comments
Open

The meaning of 'tml' in the 'dndscv.R' #80

Sunsq1997 opened this issue May 26, 2022 · 0 comments

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@Sunsq1997
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For the function mle_tcv of 'dndscv.R', does 'tml' represent a maximum likelihood estimate of the expected number of mutations (global level, not gene-specific), and I don't understand how the formula is derived. Here, what does exp_rel_neutral mean?
@Sunsq1997 Sunsq1997 changed the title The meaning The meaning of 'tml' in the 'dndscv.R' May 26, 2022
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@Sunsq1997