diff --git a/tests/local/mainUnique.ts b/tests/local/mainUnique.ts
new file mode 100644
index 00000000..aeb80a38
--- /dev/null
+++ b/tests/local/mainUnique.ts
@@ -0,0 +1,7 @@
+import path from 'path'
+import pg from 'pg'
+
+export default {
+  pathbasenamewrap: (n: any) => path.basename(n),
+  pgpoolwrap: (n: any) => pg.Pool(n)
+}
diff --git a/tests/tests-ava-tsx/esmock.ava.tsx.test.ts b/tests/tests-ava-tsx/esmock.ava.tsx.test.ts
new file mode 100644
index 00000000..1cd5fe09
--- /dev/null
+++ b/tests/tests-ava-tsx/esmock.ava.tsx.test.ts
@@ -0,0 +1,32 @@
+import test from 'ava'
+import esmock from 'esmock'
+
+test('should mock js when using tsx', async t => {
+  const main = await esmock('../local/main.js', {
+    path: {
+      basename: () => 'hellow'
+    }
+  })
+
+  t.is(main.pathbasenamewrap(), 'hellow')
+})
+
+test.failing('should mock ts when using tsx - unknown file extension', async t => {
+  const main = await esmock('../local/main.ts', {
+    path: {
+      basename: () => 'hellow'
+    }
+  })
+
+  t.is(main.pathbasenamewrap(), 'hellow')
+})
+
+test.failing('should mock ts when using tsx - invalid moduleId', async t => {
+  const main = await esmock('../local/mainUnique.js', {
+    path: {
+      basename: () => 'hellow'
+    }
+  })
+
+  t.is(main.pathbasenamewrap(), 'hellow')
+})
diff --git a/tests/tests-ava-tsx/package.json b/tests/tests-ava-tsx/package.json
new file mode 100644
index 00000000..65a7a7a3
--- /dev/null
+++ b/tests/tests-ava-tsx/package.json
@@ -0,0 +1,29 @@
+{
+  "type": "module",
+  "description": "esmock unit tests, tsx with ava",
+  "repository": {
+    "type": "git",
+    "url": "https://github.com/iambumblehead/esmock.git"
+  },
+  "dependencies": {
+    "ava": "^5.3.1",
+    "babelGeneratedDoubleDefault": "file:../local/babelGeneratedDoubleDefault",
+    "eslint": "file:../node_modules/eslint",
+    "esmock": "file:..",
+    "form-urlencoded": "file:../node_modules/form-urlencoded",
+    "sinon": "file:../node_modules/sinon",
+    "tsx": "^3.12.7"
+  },
+  "scripts": {
+    "test": "ava"
+  },
+  "ava": {
+    "extensions": {
+      "ts": "module"
+    },
+    "nodeArguments": [
+      "--loader=tsx",
+      "--loader=esmock"
+    ]
+  }
+}
diff --git a/tests/tests-ava-tsx/tsconfig.json b/tests/tests-ava-tsx/tsconfig.json
new file mode 100644
index 00000000..5b17f4eb
--- /dev/null
+++ b/tests/tests-ava-tsx/tsconfig.json
@@ -0,0 +1,8 @@
+{
+  "esm": true,
+  "compilerOptions": {
+    "allowSyntheticDefaultImports": true,
+    "module": "ESNext",
+    "moduleResolution": "node"
+  }
+}