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Question re: PFAM domains #7305

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ecerami opened this issue Mar 16, 2020 · 2 comments
Closed

Question re: PFAM domains #7305

ecerami opened this issue Mar 16, 2020 · 2 comments
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manual cBioPortal -- The Missing Manual

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@ecerami
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ecerami commented Mar 16, 2020

Does anyone recall exactly how we get the PFAM domains for each protein?

I thought it was based on the UniProt canonical sequence.

But, if you compare:

http://bit.ly/2U5UA8U

with https://pfam.xfam.org/protein/P00533

you can notice some of the domains don't line up exactly, e.g. look at the kinase domain.

@jjgao @tmazor any ideas?

@ecerami ecerami added the manual cBioPortal -- The Missing Manual label Mar 16, 2020
@inodb
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inodb commented Mar 16, 2020

@ecerami we are still on an older version of PFAM: genome-nexus/genome-nexus-importer#26

and #5691 (comment)

@ecerami
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ecerami commented Mar 16, 2020

ah, tx @inodb --> closing

@ecerami ecerami closed this as completed Mar 16, 2020
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