diff --git a/easybuild/easyconfigs/r/RELION/RELION-b5.0.0.20231031.de83020-foss-2022a-CUDA-11.7.0.eb b/easybuild/easyconfigs/r/RELION/RELION-b5.0.0.20231031.de83020-foss-2022a-CUDA-11.7.0.eb
deleted file mode 100644
index 0a1521b5aca..00000000000
--- a/easybuild/easyconfigs/r/RELION/RELION-b5.0.0.20231031.de83020-foss-2022a-CUDA-11.7.0.eb
+++ /dev/null
@@ -1,182 +0,0 @@
-# Thomas Hoffmann, EMBL Heidelberg, structures-it@embl.de, 2023/11   
-
-easyblock = 'CMakePythonPackage'
-name = 'RELION'
-versionsuffix = '-CUDA-11.7.0'
-_version_main = '5.0.0'
-_sha = 'de83020514bed78ad4c7808bccff7ffb41229cb2'
-_commitdate = '20231031'
-versionprefix = 'b'  # avoid beta to be default module.
-version = '%s.%s.%s' % (_version_main, _commitdate, _sha[:7])
-
-
-homepage = 'http://www2.mrc-lmb.cam.ac.uk/relion/index.php/Main_Page'
-description = """RELION (for REgularised LIkelihood OptimisatioN, pronounce rely-on) is a stand-
-  alone computer program that employs an empirical Bayesian approach to refine-
-  ment of (multiple) 3D reconstructions or 2D class averages in  electron cryo-
-  microscopy (cryo-EM).
-  Core module without dependencies for external tools.
- """
-
-toolchain = {'name': 'foss', 'version': '2022a'}
-toolchainopts = {'opt': True}
-
-modextravars = {
-    'RELION_MOTIONCOR2_EXECUTABLE': "$(which MotionCor3)",
-    'RELION_GCTF_EXECUTABLE': '$(which Gctf)',
-    'RELION_CTFFIND_EXECUTABLE': '$(which ctffind)',
-    'RELION_UNBLUR_EXECUTABLE': '$(which unblur)',
-    'RELION_SUMMOVIE_EXECUTABLE': '$(which summovie)',
-    'RELION_RESMAP_EXECUTABLE': '$(which ResMap)',
-    'RELION_TOPAZ_EXECUTABLE': '$(which topaz)',
-    'RELION_PYTHON_EXECUTABLE': '$(which python)',
-    'RELION_IMOD_WRAPPER_EXECUTABLE': '$(yet-another-imod-wrapper)',
-    'RELION_PDFVIEWER_EXECUTABLE': '$(which evince)',
-    # RELION_EXTERNAL_RECONSTRUCT_EXECUTABLE: set externally, e.g. sidesplitter or externprior module
-    #
-    # Adapt site specific settings:
-    'RELION_SCRATCH_DIR': '$SCRATCHDIR',
-    'RELION_QSUB_NRMPI': '3',
-    'RELION_QSUB_NRTHREADS': '7',
-    'RELION_MINIMUM_DEDICATED': '15',
-    #
-    'RELION_QSUB_EXTRA_COUNT': '7',
-    'RELION_QUEUE_USE': 'true',
-    'RELION_QUEUE_NAME': 'gpu-el8',
-    'RELION_QSUB_COMMAND': 'sbatch',
-    'RELION_QSUB_EXTRA2_DEFAULT': '60GB',
-    'RELION_QSUB_EXTRA2': 'Memory',
-    'RELION_QSUB_EXTRA1': 'GPU count',
-    'RELION_QSUB_EXTRA1_DEFAULT': '2',
-    'RELION_QSUB_EXTRA3': 'Walltime',
-    'RELION_QSUB_EXTRA3_DEFAULT': '1-0:0:0',
-    'RELION_QSUB_EXTRA4': 'Extra modules',
-    'RELION_QSUB_EXTRA4_DEFAULT': '',
-    'RELION_QSUB_EXTRA5': 'Extra slurm parameter',
-    'RELION_QSUB_EXTRA5_DEFAULT': "#SBATCH --ntasks-per-core=1",
-    'RELION_QSUB_EXTRA6': 'Preprocess command',
-    'RELION_QSUB_EXTRA6_DEFAULT': "#PREPROC: replace, if required",
-    'RELION_QSUB_EXTRA7': 'Postprocess command',
-    'RELION_QSUB_EXTRA7_DEFAULT': "#POSTPROC: replace, if required",
-    'RELION_TEMPLATES': '%(installdir)s/templates/',
-    'RELION_QSUB_TEMPLATE': '${RELION_TEMPLATES}/gpu.slurm.script',
-    #
-    'RELION_DO_OWN_MOTIONCOR': '0',
-    # use GPU by default. Requires RELION-5.0.0_env_use_gpu.patch
-    'RELION_USE_GPU_ACCELERATION': '1',
-    #
-    # 'RELION_STACK_BUFFER: '0',  # see: https://github.com/3dem/relion/pull/783
-    # 'RELION_BLUSH_ARGS' '',  # TODO
-    # 'RELION_RESMAP_TEMPLATE': ''  # resmap still required?
-    # 'RELION_SCRIPT_DIRECTORY': ''  # required for relion-it on-the-fly processing.
-    #
-}
-
-_srcdirname = '%%(builddir)s/relion-%s' % _sha
-
-source_urls = ['https://github.com/3dem/relion/archive/']
-sources = [{
-    'download_filename': '%s.tar.gz' % _sha[:7], 'filename':
-    '%(name)s-%(version)s.tar.gz'
-}]
-patches = [
-    'RELION-5.0.0_target-all-cuda-compute-capabilities.patch',
-    'RELION-5.0.0_env_use_gpu.patch',
-    'RELION-5.0.0_qsub_script_expand_env.patch',
-    # inject site specific job template into %s/templates:
-    # ('RELION-5.0.0_add_templates.patch', 0)
-]
-checksums = [
-    {'RELION-5.0.0.20231031.de83020.tar.gz': 'de15b3123028c8ada58584a070254eddd89bf67c954b555de6e6e5379f295d15'},
-    {'RELION-5.0.0_target-all-cuda-compute-capabilities.patch':
-     '3e32f380477835444ef0ccc9e8f551662208445377ef226bc67109cdb810c61e'},
-    {'RELION-5.0.0_env_use_gpu.patch': 'e7bc80f71aef9ec8bf33c095449181a9dba0f4fedfbac25e86dc6fc17fcd37da'},
-    {'RELION-5.0.0_qsub_script_expand_env.patch': '4fb8a9efdfaacc8644f39ca96815572e10f52ac1422a766d774c1827c8886519'},
-    # {'RELION-5.0.0_add_templates.patch': '...'},
-]
-
-builddependencies = [
-    ('CMake', '3.24.3'),
-]
-
-dependencies = [
-    ('Python', '3.10.4'),
-    ('SciPy-bundle', '2022.05'),
-    ('CUDA', '11.7.0', '', SYSTEM),
-    ('X11', '20220504'),
-    ('FLTK', '1.3.8'),
-    ('LibTIFF', '4.3.0'),
-    ('einops', '0.4.1'),
-    ('mrcfile', '1.4.3'),
-    ('lil-aretomo', '0.1.0'),
-    ('lru-dict', '1.2.0'),
-    ('makefun', '1.15.1'),
-    ('starfile', '0.5.1'),
-    ('ctffind', '4.1.14'),
-    ('MotionCor2', '1.5.0'),  # update to 1.6.4?
-    # PR 19123 ('MotionCor3', '1.0.1', versionsuffix),
-    # PR 19120 ('AreTomo2', '1.0.0', versionsuffix),
-    # PR 18679 ('IMOD', '4.12.17', versionsuffix),
-    ('relion-blush', '0.0.1.20231105.3148869', versionsuffix),
-    # PR 19157 ('Model-Angelo', '1.0.9', versionsuffix),
-    ('DynaMight', '0.0.0.20231107.86870f3', versionsuffix),
-    # PR 19228('topaz-em', '0.2.5.20230926', versionsuffix),
-    # ('ResMap', '1.1.4') # still required?
-    # mdocfile loaded last, because it updates typing-extensions (4.8.0)...
-    ('mdocfile', '0.1.0'),
-]
-
-configopts = "-DBUILD_SHARED_LIBS=ON "
-configopts += "-DCMAKE_SHARED_LINKER_FLAGS=-lpthread "
-configopts += "-DCUDA_ARCH='%(cuda_cc_semicolon_sep)s' "
-configopts += "-DCUDA_NVCC_FLAGS='--std=c++14' "
-configopts += "-DFETCH_WEIGHTS=OFF "  # weights provided by dependencies.
-# Setting PYTHON_EXE_PATH would explicitly set python_executable and torch_home in relion_python_scripts!
-# However, we want to use ptyhon from $PATH and $TORCH_HOME set by  DynaMight and Model-Angelo.
-
-
-# avoid hatchling requirement to install (compare genomepy-0.15.0-foss-2022a.eb)
-# (since installing it introduces conflicting version requirements with poetry included with Python)
-_preinstallopts_no_hatchling = """sed -i -e 's/^build-backend = .*/build-backend = "setuptools.build_meta"/g' """
-_preinstallopts_no_hatchling += """-e 's/^requires = .*/requires = ["setuptools"]/g' """
-_preinstallopts_no_hatchling += """-e 's/dynamic = .*/version = "%(version)s"/g' pyproject.toml && """
-
-
-exts_defaultclass = 'PythonPackage'
-exts_default_options = {'source_urls': [PYPI_SOURCE], 'download_dep_fail': True, 'use_pip': True}
-exts_list = [
-    ('morphosamplers', '0.0.9', {
-        'checksums': ['8ab44121ae1d25c1651d70e9cbcab8e49ed4b4825a1eb0560ed5a78d73907c19'],
-    }),
-    ('yet_another_imod_wrapper', '0.1.0', {
-        'preinstallopts': _preinstallopts_no_hatchling,
-        'checksums': ['2216b7fe6a97e84405704031e0a6f2fa749f1933cb92d54f574c3647b74785be'],
-    }),
-]
-
-fix_python_shebang_for = [
-    'bin/yet-another-imod-wrapper'
-]
-
-postinstallcmds = [
-    "sed -i 's/^dynamic = .*version.*/version = \"%s\"/g' %s/pyproject.toml" % (_version_main, _srcdirname),
-    "sed -i 's/^.tool.setuptools_scm./#&/g' %s/pyproject.toml" % _srcdirname,
-    "cd %s/ &&pip install . --no-deps --ignore-installed --prefix=%%(installdir)s" % _srcdirname,
-    'mkdir -p %(installdir)s/templates',
-    'cp %s/templates/* %%(installdir)s/templates' % _srcdirname,
-    'sed -i "s|SED_MODULENAME|%(module_name)s|g" %(installdir)s/templates/*'
-]
-
-sanity_pip_check = True
-
-sanity_check_paths = {
-    'files': ['lib/librelion_gui_lib.%s' % SHLIB_EXT, 'lib/librelion_jaz_gpu_util.%s' % SHLIB_EXT],
-    'dirs': [
-        'bin',
-        # 'templates'
-    ]
-}
-
-options = {'modulename': False}
-
-moduleclass = 'bio'