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DESCRIPTION
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DESCRIPTION
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Package: simtrial
Type: Package
Title: Clinical Trial Simulation
Version: 0.4.2
Authors@R: c(
person("Keaven", "Anderson", email = "[email protected]", role = c("aut")),
person("Yujie", "Zhao", email = "[email protected]", role = c("ctb","cre")),
person("John", "Blischak", role = c("ctb")),
person("Nan", "Xiao", role = c("ctb")),
person("Yilong", "Zhang", role = c("aut")),
person("Jianxiao", "Yang", role = c("ctb")),
person("Lili", "Ling", role = c("ctb")),
person("Xintong", "Li", role = c("ctb")),
person("Ruixue", "Wang", role = c("ctb")),
person("Yi", "Cui", role = c("ctb")),
person("Ping", "Yang", role = c("ctb")),
person("Yalin", "Zhu", role = c("ctb")),
person("Heng", "Zhou", role = c("ctb")),
person("Amin", "Shirazi", role = c("ctb")),
person("Cole", "Manschot", role = c("ctb")),
person("Merck & Co., Inc., Rahway, NJ, USA and its affiliates", role = "cph")
)
Description: Provides some basic routines for simulating a
clinical trial. The primary intent is to provide some tools to
generate trial simulations for trials with time to event outcomes.
Piecewise exponential failure rates and piecewise constant
enrollment rates are the underlying mechanism used to simulate
a broad range of scenarios such as those presented in
Lin et al. (2020) <doi:10.1080/19466315.2019.1697738>.
However, the basic generation of data is done using pipes to allow
maximum flexibility for users to meet different needs.
License: GPL-3
URL: https://merck.github.io/simtrial/, https://github.com/Merck/simtrial
BugReports: https://github.com/Merck/simtrial/issues
Encoding: UTF-8
LazyData: true
VignetteBuilder: knitr
Depends: R (>= 4.1.0)
Imports:
Rcpp,
data.table (>= 1.12.4),
doFuture,
foreach,
future,
methods,
mvtnorm,
stats,
survival,
utils,
gsDesign2 (>= 1.1.3)
Suggests:
Matrix,
covr,
dplyr,
ggplot2,
gsDesign,
gt,
knitr,
rmarkdown,
survMisc,
survRM2,
testthat,
tidyr
LinkingTo:
Rcpp
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.2