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Releases: Kalan-Lab/zol

v1.4.11

26 Jul 15:23
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  • correct issue with cpus argument for pyhmmer being accidentally renamed to threads in the switch of terminology from cpus to threads for zol code made in v1.4.10
  • add option to skip annotations in zol, --skip-annotations
  • add shebang in annotateProtaSeqs.py to make it executable.

Full Changelog: v1.4.10...v1.4.11

v1.4.10

12 Jul 21:50
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minor updates

  • update and further polish arguments (e.g. underscores to dashs).
  • add --small-genomes preset flag for skani based dereplication in zol.
  • (for bioconda) planning on adding constraints on versions for some dependencies (e.g. muscle>=5.0)
    Full Changelog: v1.4.9...v1.4.10

v1.4.9

09 Jul 02:45
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  • Add small script for standalone annotation using zol's standard annotation approach for consensus sequences of ortholog groups called annotateProtSeqs.py.

What's Changed

Full Changelog: v1.4.8...v1.4.9

v1.4.8

04 Jul 21:19
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  • re-configure where multiprocessing.set_start_method() is set in fai and add catches for possible issues to work as intended on newer Macs.
  • add cgc command to tests

What's Changed

Full Changelog: v1.4.7...v1.4.8

v1.4.7

03 Jul 20:16
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  • Update usage of pomegrenate for HMM mode in fai for finding gene clusters to account for API changes.
  • This is largely to update versions for some dependencies (mainly biopython and pomegrenate) in bioconda to assist in the transition to newer python versions.

v1.4.6

03 Jul 03:01
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  • add option to provide pre-computed ortholog group designations for locus tags in zol.

v1.4.5

13 Jun 02:03
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  • make inputting gene clusters to zol more flexible.
  • change defaults to quicker and lower memory usage: default alignment mode is now super5 in MUSCLE and calculation of BetaRD-gc statistics are now only performed if requested via the -b argument.
  • clean up more temporary files in the subdirectory for determining ortholog groups in zol.
  • add note on computational resource requirements in README.

What's Changed

Full Changelog: v1.4.4...v1.4.5

v1.4.4

07 Jun 14:23
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  • bump version twice to v1.4.4 - creating new release to have correct version reflected in bioconda
  • deleted releases v1.4.2 and v1.4.3 from github (they are still available on Zenodo)

Major updates in v1.4.2 included:

  • introduce the cgc program for large scale summary visualization of homologous gene cluster instances
  • introduce the salt program for determining signatures of support for horizontal/lateral transfer following fai based identification of gene cluster instances.
  • small updates throughout but no major alterations to the core functionalities.

Full Changelog: v1.4.3...v1.4.4
Full Changelog: v1.4.1...v1.4.2

v1.4.1

19 May 16:02
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  • revert to non-parallelized splitting of DIAMOND alignment results in findOrthologs.py.

Full Changelog: v1.4.0...v1.4.1

v1.4.0

14 May 21:56
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  • Correct fai cutoff for minimum proportion of distinct query genes to properly account for the occurrence of intermediate/background genes. The calculation reported in spreadsheets was not affected.
  • Set default syntenic correlation threshold to 0.0 (off) from previous default of 0.6.
  • Update prepTG to reference data from GTDB R220 and allow users the option to choose GTDB release (>= R214 supported).
  • Update splitting of DIAMOND alignment in zol to allow for parallelization.
  • Introduce CD-HIT protein clustering option/mode instead of the default InParanoid-like approach.
  • Add option to control re-inflation CD-HIT parameters.
  • New scripts and tutorial on using fast.genomics and CAGECAT to get sets of homologous gene clusters to investigate in zol.