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<!DOCTYPE html>
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<img class="d-block img-fluid" src="images/carousel_photos/Figure_biomaterial_home.jpg" alt="">
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<h3 style="color: white;">Biomaterial</h3>
<p>We develop innovative biomaterials that can be used to <br> treat injuries or replace damaged
tissues.</p>
</div>
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<h3 style="color: white;">Tissue Engineering</h3>
<p>We design and tune 3D composite scaffolds to provide <br> an optimal microenvironment for
encapsulated cells to develop tissue.</p>
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<h3 style="color: white;">Cancer Immunology & Nanomedicine</h3>
<p>We are exploring new frontiers in using the immune system to target cancer.</p>
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<br>
<center>
<h5 style="padding-left: 3%; padding-right: 3%; font-weight: bold;">We develop novel biotechnologies for
clinical translation
based on the <br> understanding of underlying biological mechanisms and disease pathology.</h5>
</center>
<br>
<section class="ftco-section services-section bg-light" id="about">
<div class="container">
<center>
<h2 class="mb-4">About Us</h2>
</center>
<p style=" color: black;" class="p_about">Welcome to the Center for Engineered Therapeutics – Clinical
Translation of Discoveries from Engineering in Medicine. Our mission is to develop novel biotechnologies
to overcome currently incurable diseases and injuries, with the end goal of achieving life extension and
overcome ageing. We study biology to define important medical questions and use principles of
engineering in medicine to realize rigorous therapeutics and enhance the efficacy and safety of
engineered therapeutics in the clinic.
</p>
<p style=" color: black;" class="p_about">Our center is located within the rich ecosystem of the Department
of Medicine, Brigham and Women's Hospital,
Harvard Medical School, and the Harvard-MIT Division of HST. We have an interdisciplinary research
environment where engineers, biologists, chemists, physicists, pharmacists, material
scientists, and clinicians work together to solve biological challenges in holistic and creative
approaches. We love exciting and hard problems that will have an impact on patient's lives.
</p>
<br><br><br>
</div>
<center>
<h2>Featured Publications<h2>
</center>
<br><br>
<center>
<table class="table-responsive" cellpadding="10px">
<tr>
<td align="center"><a href="https://www.nature.com/articles/s41551-019-0470-8" target="blank"><img
src="images/journal_images/n_bmed_19.png"></a></td>
<td align="center"><a href="https://www.nature.com/articles/s41565-019-0494-y" target="blank"><img
src="images/journal_images/n_nano_19.png"></a></td>
<td align="center"><a href="https://www.nature.com/articles/s41551-018-0254-6/" target="blank"><img
src="images/journal_images/n_biomed_18.jpg"></a></td>
</tr>
<tr>
<td>
<hr id="newhr">
</td>
<td>
<hr id="newhr">
</td>
<td>
<hr id="newhr">
</td>
</tr>
<tr style="color: black;">
<td align="center" width="33%">Computationally designed antibody-drug conjugates self-assembled via
affinity ligands</td>
<td align="center" width="33%">Transcellular transfer of nanomedicine</td>
<td align="center" width="33%">A designer self-assembled supramolecule amplifies macrophage immune
responses against aggressive cancer</td>
</tr>
<tr>
<td>
<hr id="newhr">
</td>
<td>
<hr id="newhr">
</td>
<td>
<hr id="newhr">
</td>
</tr>
<tr>
<td><br></td>
</tr>
<tr>
<td align="center"><a href="https://www.pnas.org/content/113/15/E2104" target="blank"><img
src="images/journal_images/pnas.jpg"></a></td>
<td align="center"><a href="https://www.nature.com/articles/ncomms7139" target="blank"><img
src="images/journal_images/n_comm_1.png"></a></td>
<td align="center"><a href="https://www.nature.com/articles/ncomms7169" target="blank"><img
src="images/journal_images/n_comm_2.jpg"></a></td>
</tr>
<tr>
<td>
<hr id="newhr">
</td>
<td>
<hr id="newhr">
</td>
<td>
<hr id="newhr">
</td>
</tr>
<tr style="color: black;">
<td align="center" width="33%">Reporter nanoparticle that monitors its anticancer efficacy in real
time</td>
<td align="center" width="33%">Temporally sequenced anticancer drugs overcome adaptive resistance by
targeting a vulnerable chemotherapy-induced phenotypic transition</td>
<td align="center" width="33%">Predicting clinical response to anticancer drugs using an ex vivo
platform that captures tumour heterogeneity</td>
</tr>
<tr>
<td>
<hr id="newhr">
</td>
<td>
<hr id="newhr">
</td>
<td>
<hr id="newhr">
</td>
</tr>
<tr>
<td><br></td>
</tr>
<tr>
<td align="center"><a href="https://pubs.acs.org/doi/abs/10.1021/acsnano.6b00320"
target="blank"><img src="images/journal_images/acsnano.jpg"></a></td>
<td align="center"><a href="https://pubs.acs.org/doi/full/10.1021/acsnano.6b01600"
target="blank"><img src="images/journal_images/acsnano2.jpg"></a></td>
<td align="center"><a href="https://pubs.acs.org/doi/abs/10.1021/acsnano.6b00241"
target="blank"><img src="images/journal_images/acsnano3.jpg"></a></td>
</tr>
<tr>
<td>
<hr id="newhr">
</td>
<td>
<hr id="newhr">
</td>
<td>
<hr id="newhr">
</td>
</tr>
<tr style="color: black;">
<td align="center" width="33%">Rationally Designed 2-in-1 Nanoparticles Can Overcome Adaptive
Resistance in Cancer</td>
<td align="center" width="33%">Combining Immune Checkpoint Inhibitors and Kinase-Inhibiting
Supramolecular Therapeutics for Enhanced Anticancer Efficacy</td>
<td align="center" width="33%">Algorithm for Designing Nanoscale Supramolecular Therapeutics with
Increased Anticancer Efficacy</td>
</tr>
<tr>
<td>
<hr id="newhr">
</td>
<td>
<hr id="newhr">
</td>
<td>
<hr id="newhr">
</td>
</tr>
</table>
<br>
<br>
<a href="publications.html"><button type="button" class="btn btn-dark" style="border-radius: 0%;">All
Publications</button></a>
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<p>Copyright © 2019 Center For Engineered Therapeutics | All rights reserved</p>
<p>Made by <a href="https://www.linkedin.com/in/itsron143/">Rounak</a>, <a
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